Affiliation:
1. Mahathma Gandhi College Affiliated to University of Kerala, Thiruvananthapuram, India.
Abstract
A Bistable RNA pairs have noteworthy importance in RNA ribo-switches, RNA thermometers and viroid replications, making this molecule particularly interesting to chemists and scientists working in field of biochemistry, virologists and computational chemistry. It adopts equilibrium between two distinct hairpin conformations. The two hairpin conformations adopt different functionality. In this review paper, we discuss the pathways used by bistable RNAs for switching confirmations and look into the future possibilities existing mechanisms can yield in RNA and retro-virus RNA studies.
Publisher
Oriental Scientific Publishing Company
Subject
Drug Discovery,Environmental Chemistry,Biochemistry,General Chemistry