Development and validation of novel spectrophotometric methods for the determination of ethacridine lactate in bulk-Reference-Cited by-同舟云学术

Development and validation of novel spectrophotometric methods for the determination of ethacridine lactate in bulk

Published:2010-02-08 Issue:2 Volume:7 Page:487-490
ISSN:0973-3469
Container-title:Material Science Research India
language:
Short-container-title:Mat Sci Res India

Author:

Venumadhav E.¹,Praveen P. Sai²,Neha T.²,Bhargavi P.²,Rao G. Devela²

Affiliation:

1. Cheif Operating Officer, Veeda CR, Ahmedabad, Gujarat, India.

2. KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada - 520 010, India.

Abstract

Three simple and sensitive visible spectrophotometric methods (A-C) for the determination of Ethacridine Lactate in pure samples and pharmaceutical formulations are described. They are based on the formation of colored species by treating with Folin-Ciocalteau reagent (Method A, λmax 600nm) or 3-methyl 2-benzathiazolinone hydrazone in the presence of Ferric chloride (Method B, λmax 580 nm), or 1, 10 Phenathroline in presence of Ferric chloride (Method C, λmax 490nm). These methods were extended to the analysis of pharmaceutical preparations and results are compound with the refernce method (USP).

Publisher

Oriental Scientific Publishing Company

Subject

Pharmacology (medical),Complementary and alternative medicine,Pharmaceutical Science

Reference10 articles.

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