Association of the Red Cell Distribution Width with Complete Blood Count, Glycated Hemoglobin and Vitamin D in Patients with Type 2 Diabetes Mellitus- Across Sectional Study

Abstract

The current study was aimed to assess the association of the Red Cell Distribution Width (RDW) with Glycated haemoglobin (HbA1C) and Vitamin D in Patients with Type 2 Diabetes Mellitus to provide insight into the potential physiological mechanisms and predictive significance of RDW fluctuations in patients with heart failure who are diabetic. Material &Methods: The cross-sectional design of this study was utilized to investigate a cohort of 150 patients who had received a diagnosis of type 2 diabetes mellitus. The assessment centered on the evaluation of comorbidities, red cell distribution width (RDW), and glycemic management in addition to vitamin D levels. Information was gathered via questionnaires, encompassing demographic details as well as medical history. Blood samples were assessed for RDW, total blood count, HbA1c, and Vitamin D concentrations using automated analyzers. The statistical analysis was performed utilizing version 27 of SPSS. Results: The study found low relationships between HbA1c and Vitamin D (r = -0.033, p = 0.691), RDW and HbA1c (r = -0.046, p = 0.573), and RDW and Vitamin D (r = -0.128, p = 0.118). Furthermore, Vitamin D had diverse connections with CBC values, suggesting a complex link within the setting of type 2 diabetes mellitus. Conclusion: The findings of the current study indicated an association between the RDW and RBCs, Hb and Red blood cell indices (HCT, MCV, MCH and MCHC) in patients with T2DM. The RDW could therefore serve as potential marker for the management of patients with T2DM.