Antimicrobial Activities of Schiff Base Metal Complexes of First Transition Series-Reference-Cited by-同舟云学术

Antimicrobial Activities of Schiff Base Metal Complexes of First Transition Series

Published:2021-10-27 Issue:3 Volume:18 Page:575-583
ISSN:2456-2602
Container-title:Biosciences Biotechnology Research Asia
language:en
Short-container-title:Biosci., Biotech. Res. Asia

Author:

Laiq Esmat¹^ORCID,Shahid Nida²^ORCID

Affiliation:

1. 1Chemistry Section, Women’s College, Department of chemistry, Aligarh Muslim University, Aligarh, India– 202002

2. 2Department of chemistry, Arya Mahilla (P.G.) College, Shahjahanpur, India,-242001

Abstract

The correlative antimicrobial analysis of amino acid Schiff base and derivatized tren metal complexes: A= [MLCl2], B= [ML(CH3OH)2], respectively, against fungal strains, Candida parapsilosis, Candida albicans, Candida krusei, and Cryptococcus neoformans and (Gram-negative) P. aeruginosa, E. coli, S. typhimurium, and S. pyogenes, Methicillin-resistant Staphylococcus aureus (MRSA), S. mutans (Gram-positive) bacterial strains had been done by disk diffusion method following McFarland protocol. [CuLCl2] and [Cu (CH3OH)2] manifest overwhelming activity against microbes than other metal complexes of cobalt, nickel and zinc. Minimum inhibition concentration data also shows that copper complexes have the lowest MIC values against these tested microorganisms. The significance of this investigation is to uncover shielding and constructive therapeutic agents that wield against bacterial and fungal infection.

Publisher

Oriental Scientific Publishing Company

Subject

Drug Discovery,Agronomy and Crop Science,Biotechnology

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