Microwave Assisted Synthesis and Characterization of 4-Aminothiophenol with Two Mixed Ligands Chelates of Cobalt, Nickel and Mercury

Abstract

Amino compounds are widely used in medicine, pharmacy, dyes, and industries. In coordination chemistry, these compounds are biologically important. The cobalt, nickel, and mercury metal chelates are derived from 4-aminothiophenol with two mixed ligands, namely sodium benzoate and sodium nitrite. These metal chelates synthesized were characterized by microanalysis, metal estimation, conductivity, magnetic property, Ultraviolet-Visible, Fourier Transform-Infra Red, NMR (proton and carbon), and X-ray diffraction (Powder method). The analytical data show that the metal ligand stoichiometric ration of cobalt and nickel complexes and mercury complexes was confirmed. All the metal chelates were found to be monomeric, neutral, and non-electrolytic. The IR spectral data results show that the 4-ATP acts as monodentate, which can coordinate through the amino group, and another mixed ligand coordinates through the oxygen atom. The results of UV-visible and magnetic studies predict the octahedral geometry of the cobalt, nickel, and tetrahedral geometry of the mercury complex. The 1H-NMR and 13C-NMR spectra and XRD (Powder pattern) indicate the diamagnetic nature, geometry, crystal structure, and size of the mercury complex. The metal chelates were screened for their biological activities using the Agar disc diffusion. The MIC values that indicate their bio-potential character were found.