Macrocycliczinc(II) Complexes with Tetradentate N2O2 Donor Schiff Base Ligands Incorporating 1,3,4-Thiadiazole Ring

Abstract

A new series ofdiazadioxamacrocycliczinc(II) derivatives [{Zn(M)(H2O)2}(OAc)2] (M= macrocyclic ligands) prepared via template synthesis method, by the reaction of Schiff bases derived from bis-(2-hydrazino-1,3,4-thiadiazole-5-yl)arene/alkanes and 3,5-dichlorosalicyldehyde/2-hydroxy-1-naphthaldehyde with 1,4-dibromobutane in the presence of Zn(II) ion. The structures of all these complexes were established on the basis of elemental analyses, spectral data (IR and 1H-NMR), PXRD, SEM techniques. Presence of coordinated water molecules in the Zn(II) complexes were confirmed by TGA analyses. The antimicrobial effects of all the synthesized complexes were evaluated against different species of pathogenic fungi (A. niger, A. alternata ) and bacteria (E. coli, B. subtilis).