Gel Formulation of Jamblang Leaf Extract (Syzygium cumini L) Skeel and Antioxidant Activity

Author:

Samsuar Samsuar1,Hanifa Dina1

Affiliation:

1. Department of Fharmacy, Faculty of Mathematics and Natural Science, Universitas Tulang Bawang Lampung, Bamdar Lampung Indonesia.

Abstract

In this paper we reported gel formulation that containing Jamblang Leaf extract (Syzygium cumini L) and activity test as antioxidant. The Jamblang Leaf plant contained polyphenols compound which function as antioxidants. The purpose of this study was to determine the antioxidant activity of gel formulation that containing jamblang leaf extract. Extraction of Jamblang Leaf were formulated with three varation of concentration and gel basis as negative controls. The gel formulation were evaluated for organoleptic observations, homogeneity, pH, viscosity, dispersion test, adhesion test, accelerated stability test for 4 weeks storage, and measurement of antioxidant activity was carried out using the DPPH method with wavelength of 519 nm. The results of gel formulation IC50 value shows the ability of a substance to inhibit 50% DPPH radical of 47.735 ppm. The gel extract of Jamblang Leaf has a very strong antioxidant activity.

Publisher

Oriental Scientific Publishing Company

Subject

Drug Discovery,Environmental Chemistry,Biochemistry,General Chemistry

Reference17 articles.

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4. 4. Ratnayani, “Kadar Total Senyawa Fenolat Pada Madu Randu Dan Madu Kelengkeng Serta Uji Aktivitas Antiradikal Bebas dengan Metode DPPH.,” Jurnal Kimia, vol. 6, no. 2, p. 164. (2012)

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