Short Term Evaluation Biological Bone Reconstruction for Tibia Distal Osteosarcoma

Abstract

Introduction: Limb salvage in children with primary malignant bone tumors in lower extremity is challenging, with considerations such as shortening, bone and joint remodeling and high functional demands of active children. We adopted a biological approach by preserving the patient native joint, with bony defects bridged by autologous tibial biological grafts.Presentation of Case: A 16-year-old female with pain in the left lower leg and was diagnosed with a tibial distal osteosarcoma. The patient was perform preoperative chemotherapy and had a good result. This was assessed clinically by a decrease in the size of the swelling and pain from the tumor, and radiological. Then she underwent wide excision surgery, we decided to perform biological reconstruction with pasteurized technic, and evaluation after 3 month (union, early weight bearing and rehabilitation).Discussion: We found that biological reconstruction using pasteurized technic with autologous tibial biological grafts is a viable option in children with high grade osteosarcoma in lower extremity. It provides immediate stability, allows early weight bearing and early rehabilitation. Time to full weight bearing is shorter than prosthetic replacement. Use of autologous tibial biological grafts has lower cost, no rejection because the patient’s own tissue is used, exact anatomical matching and no donor morbidity.Keyword: biological bonegraft, pasteurized, osteosarcoma.