Clinical Presentation of Hemoglobin C in Albania: Case Series-Reference-Cited by-同舟云学术

Clinical Presentation of Hemoglobin C in Albania: Case Series

Published:2022-10-05 Issue:B Volume:10 Page:2220-2224
ISSN:1857-9655
Container-title:Open Access Macedonian Journal of Medical Sciences
language:
Short-container-title:Open Access Maced J Med Sci

Author:

Refatllari Etleva,Heta Nevila^ORCID,Barbullushi Alma,Lame Helena^ORCID,Korita Irena^ORCID,Bulo Anyla

Abstract

The presence of HbC is a rare event in Europe and Mediterranean region where thalassemia and HbS are more frequently encountered. The rarely diagnosed cases are linked with the migration from West-Central Africa. Albania is one of the Mediterranean countries where inherited haemoglobin disorders are considerably widespread. Studies have shown the presence of thalassemia, sickle cell disease and sporadic cases of Hb O-Arab, Hb Lepore especially in the areas where malaria has been endemic. In 2006 we identified the first case with HbSC disease and until 2020 we have found 15 cases with HbC variant. In this study we have collected and analyzed the laboratory and clinical data of HbC cases. Our data support reports that HbC combinations with HbS and beta thalassemia are clinically important. Our data confirm the presence of the HbC variant in ex-malaric areas where thalassemia and HbS are quite widespread.

Publisher

Scientific Foundation SPIROSKI

Subject

General Medicine

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