Factors Influencing Recurrence Rate and Survival of Patients with Colorectal Metastases after Liver Resection

Abstract

BACKGROUND: Early recurrence implies low percentage of long survival, whereas the opportunity for re-resection in selected patients represents optimal treatment with long survival. The total 5-year survival rate after hepatectomy is up to 50%, with a number of factors that are independent clinical predictors of long survival. AIM: This study aims to analyze the patient’s data from the clinic of general and hepatobiliary surgery in Aleksandrovska Hospital in Sofia, Republic of Bulgaria, in the treatment of patients with colorectal metastases of the liver and to determine the survival factors in those patients. MATERIALS AND METHODS: A retrospective study was conducted between of January 1st, 2006 and December 31st, 2015. A total of 239 patients were included: 179 patients were treated with radical operation, 5 with palliative intervention, while 55 operative explorations were performed. RESULTS: The type and the extent of resection do not affect the occurrence of local recurrence. The size, number, and metastase localization do not affect the occurrence of intrahepatic recurrence but showed characteristics of significant predictors in cumulative and mean survival. CONCLUSION: Metastases type, number and localization and metastases in lymphatic nodes and other organs were determined as predictors of long survival of patients with colorectal metastases after resection.