Correlation between Vitamin D and Uric Acid in Menopausal Women

Abstract

Background : Vitamin D deficiency and hyperuricemia are global health problems in post-menopausal women in which parathyroid hormone increases hyperuricemia incidence. Aim : This research purpose to  determine correlation between vitamin D and uric acid levels in postmenopausal women Methods: This research is an observational analytic study with a cross-sectional study design conducted at University of North Sumatra Hospital and Network Hospital in Medan for 12 months on 40 postmenopausal women who met inclusion and exclusion criteria. The data will be analyzed descriptively to determine variables frequency distribution. Previously, normality test of numerical data is carried out. If the data is normally distributed, Pearson correlation test will be carried out, and if the data is not normally distributed, then Spearman correlation test will be used. Results : Mean vitamin D of the sample was 23.11 ng/mL with a standard deviation 4.43 and median value 23.5 ng/mL. while the mean uric acid was 7.52 mg/dL with a standard deviation 0.92 and median value 7.45 mg/dL. There is an inverse relationship between uric acid levels and Vitamin D, as evidenced by Pearson test correlation coefficient of -0.541 with p value = 0.001. Conclusion : There is an inverse correlation between Vitamin D and uric acid levels.