The Diagnostic Value of the Osteoporosis Self-assessment Tool for Asians in Vietnamese Postmenopausal Women

Abstract

Introduction: Osteoporosis is a common disease that affects many women in the postmenopausal period. Dual-energy X-ray absorptiometry (DXA) is a simple and noninvasive method used to diagnose osteoporosis. The Osteoporosis Self-Assessment Tool for Asians (OSTA) is an osteoporosis risk assessment toolkit, used for menopausal women in Asia. This study aimed to evaluate the diagnostic values of the OSTA index in determining the risk of osteoporosis in postmenopausal women. Material and Methods:  This cross-sectional study was conducted on 919 postmenopausal women to determine the value of OSTA in osteoporosis risk assessment. The bone density was measured using the DXA method in the lumbar spine and femoral neck. Results: Based on the ROC curve, the sensitivity and specitivity of OSTA were 70.3% and 63.6% at the cut-off of ≤ -1.4 at the femoral neck or lumber spine or both (p = 0.005) . At a cut-off point of ≤-1 at one of two position or both, the OSTA index showed a specificity of 87.23%, sensitivity of 66.08%, positive predictive value of 46.90%, and negative predictive value of 93.78% in predicting the osteoporosis risk. Conclusions: The OSTA index is a simple tool that is highly sensitive and specific in predicting the risk of osteoporosis in postmenopausal women.