Clinical and Demographic Characteristics of Patients with COVID-19 Who Died in Modarres Hospital

Abstract

BACKGROUND: Novel coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome-CoV2 as a century concern affecting public health. AIM: This study aimed to find the clinical and demographic characteristics of the patients died following COVID-19 development at Modarres Hospital, Tehran, Iran. METHODS: In this descriptive-analytical cross-sectional study, 62 patients died following COVID-19 were studied in terms of age, gender, body mass index, comorbidity, symptoms, liver profile, lipid profile, hemoglobin, platelet, white blood cell, lymphocytes, neutrophils, C-reaction protein, polymerase chain reaction (PCR), creatine phosphokinase, creatinine, blood urea nitrogen (BUN), potassium, magnesium, and sodium. RESULTS: The results showed that 71% of patients were male and 69.4% had positive PCR test indicating low sensitivity of the test; 90.3% of patients were above 60 years old; 56.5 of patients had lymphocytopenia; the mean age was 67.62 ± 15.07 years; with symptoms lasting 6.24 days. The mean serum creatinine and BUN were 3.18 g/dl and 125.9 mg/dl, respectively, indicating renal involvement. All patients had pulmonary involvement accompanied by other organ involvements. Regarding symptoms, 72% of patients showed fever. Some affected patients had diarrhea, lethargy, and fatigue. A comparison of comorbidities by gender showed no significant differences. CONCLUSION: According to our results, the majority of patients were overweight. In people who are more than 60 years, multi-organ failure was notable. Fever, cough, and shortness of breath were dominant symptoms like other studies, but neurological complications following COVID-19 as meningoencephalitis is possible that can be used as a differential diagnosis. We did not found differences between male and female regarding comorbidity, symptoms, and mortality rate.