Analysis of 5-Year Survival Rate after Surgery for Non-Small-Cell Lung Cancer in Women

Abstract

Abstract Background: Lung cancer is the leading cause of death in men and women worldwide. The average five-year survival rate for patients with lung cancer is 22% and is significantly lower than the survival rate for other cancers. Aim: The aim of the study was to determine the five-year survival rate in women after surgery for non-small cell lung cancer. Methods: A prospective cohort study was performed on 59 operated women with primary lung cancer for the period 2011-2020 in the "Second Surgical Clinic" - University Hospital "St. George" and in the Department of "Special Surgery" - Medical University, Plovdiv. Five-year survival rate was calculated using the Kaplan-Meier method and the Life-tables method. Results: The mean age of the study group was 58.51 ± 10.84. Out of 59 operated patients, 39 (66.1%) survived and 20 (33.9%) survived the follow-up period. The group with the highest survival rate was in the IA stage - 53.14 months (4.42 years). This group has also the lowest mortality rate. The five-year survival at this stage was 71.4%. In stage IV, 57.1% of the patients survived a 60-month period, and in stage IIA and IIB, 42.9% and 33.3%, respectively. In stage IIIA is the largest number of operated patients. The five-year survival rate in this group was 25%. In stage IV, a five-year survival rate of 12.5% ​​was reported. Conclusions: The five-year survival of women operated on for lung cancer depends on the stage at which the disease is diagnosed and the extent of surgery.