Author:
Maulana Reza Achmad,Fulyani Faizah,Anjani Gemala
Abstract
Incidence of diabetes are common among population around the world. Diabetes may lead to other complication and increasing morbidity and mortality. Many ways have been done to treat and prevent the development of diabetes. In addition of conventional pharmacotherapy, therapeutic therapy shown good opportunity to maintain and improve diabetic conditions. Vitamin D3 is known as nutraceutical and has good opportunity to develop the medication of type 2 diabetes. In another way, vitamin D3 naturally easy to damage by environmental condition. To overcome this weakness, researcher around the world have developed the method for protecting unstable compound as vitamin D3 with encapsulation. Liprotide is one of the various materials which can be used for encapsulation. Combination of lipid and protein molecules is expected to be a carrier and protector of vitamin D3 in gastrointestinal system. Here we review the research advances of liprotide as nanocarriers and vitamin D3 as nutraceuticals to discuss in applied on type 2 diabetes.
Funder
Kementerian Riset Teknologi Dan Pendidikan Tinggi Republik Indonesia
Publisher
Scientific Foundation SPIROSKI
Reference100 articles.
1. IDF Diabetes Atlas; 2019. Available from: https://idf.org/e-library/epidemiology-research/diabetes-atlas.html [Last accessed on 2021 Apr 25].
2. Riskesdas K. Main Results of Basic Health Research (RISKESDAS). Vol. 44. Indonesian Health Ministry; 2018.
3. Nasr MH, Hassan BA, Othman N, Karuppannan M, Abdulaziz NB, Mohammed AH, et al. Prevalence of Vitamin D deficiency between Type 2 diabetes mellitus patients and non-diabetics in the Arab Gulf. Diabetes Metab Syndr Obes. 2022;15:647-57. https://doi.org/10.2147/DMSO.S350626 PMid:35250286
4. Amrein K, Scherkl M, Hoffmann M, Neuwersch-Sommeregger S, Köstenberger M, Berisha TA, et al. Vitamin D deficiency 2.0: An update on the current status worldwide. Eur J Clin Nutr. 2020;74(11):1498-513. https://doi.org/10.1038/s41430-020-0558-y PMid:31959942
5. Divakar U, Sathish T, Soljak M, Bajpai R, Dunleavy G, Visvalingam N, et al. Prevalence of Vitamin D deficiency and its associated work-related factors among indoor workers in a multi-ethnic southeast asian country. Int J Environ Res Public Health. 2020;17(1):164. https://doi.org/10.3390/ijerph17010164 PMid:31881679