Clinical variety of affective, sleep and motor manifestations in craniocervical dystonia (a literature review)

Author:

Khaiatova Z. G.1,Zalyalova Z. A.2

Affiliation:

1. Kazan State Medical University

2. Kazan State Medical University; Kazan State Medical University, Republican clinical diagnostical center of extrapyramidal disorders and botulinotherapy

Abstract

Recent research data literature indicates the presence of non-motor symptoms in patients with dystonia such as mood disorders, cognitive impairments, sleep disturbances, autonomic dysfunction and / or pain, which are important components of quality of life. The article discusses possible comorbidity of affective manifestations,sleep disorders and dystonia. Currently, evidence is controversial, and the question requires further study. Affective symptoms and sleep disturbances of dystonia are now recognized as the greater determinant of quality of life in dystonia, being associated with health and disability, although their contribution to the clinical picture of the disease often remains underestimated. It becomes important to identify these manifestations, assess their severity and impact on the daily activity of patients with craniocervical dystonia.

Publisher

V.M. Bekhterev National Research Medical Center for Psychiatry and Neurology

Reference81 articles.

1. Zalyalova ZA. Modern classifications of muscular dystonia, treatment strategy. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2013;113(3):85-89. (In Russ.).

2. Zakharov DV, Zalyalova ZA, Fursova IV, Yakovleva LA. Application of botulinum toxin type А in the treatment of painful dystoniain Parkinson’s disease. Obozrenie psihiatrii i medicinskoj psihologii im. V.M. Bekhtereva. 2014;(1):90-95. (In Russ.).

3. Krasnov MYu, Timerbaeva SL, Illarioshkin SN. Genetics of hereditary forms of dystonia. Annaly` klinicheskoj i e`ksperimental`noj nevrologii. 2013;7(2):55-62. (In Russ.).

4. Orlova O.R. Fokal`ny`e distonii: klinika, patogenez, lechenie s ispol`zovaniem toksina botulizma. Avtoref. dis. dokt. med. nauk. M.,2000;48. (In Russ.).

5. Orlova OR. Focal dystonia: modern approaches to diagnosis and possibilities of botulinum therapy. Nervny`e bolezni. 2016;4:3-13. (In Russ.).

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