Anhedonia as a basic syndrome and a target for treatment for depressive disorder

Author:

Mazo G. E.1,Kibitov A. O.2

Affiliation:

1. V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology

2. V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology; V.P. Serbsky National Medical Research Center on Psychiatry and Addictions

Abstract

The article presents an analytical review aimed at determining the effect of anhedonia on the course and therapeutic prognosis of depression. Currently, there is no specific pharmacological approach to the treatment of anhedonia in depression.It is clear all antidepressants that affect the symptoms of depression in general act to a certain extent on anhedonia. Modern views on the biological mechanisms involved in the formation of anhedonia are described, on the basis of which a search for drugs with anti-anhedonic activity is possible. Vortioxetine can be considered as an antidepressant with a specific anti-anhedonic effect.

Publisher

V.M. Bekhterev National Research Medical Center for Psychiatry and Neurology

Reference95 articles.

1. Депрессия и риск развития соматических заболеваний. Руководство для врачей (под редакцией Незнанов Н.Г., Мазо Г.Э., Кибитов А.О.) — М. Спец. Изд-во мед. кн., 2018; 248. [Depressiya i risk razvitiya somaticheskikh zabolevani. I. Rukovodstvo dlya vrachei (pod redaktsiei Neznanov N.G., Mazo G.E., Kibitov A.O.) — M. Spets. Izdatel’stvo med.kn., 2018; 248.] (In Russ.)

2. Мазо Г.Э., Незнанов Н.Г. Депрессивное расстройство/– М. ГЭОТАР–Медиа, Москва. — 2018. — 112с. (Серия «Библиотека врача-специалиста») [Mazo G.E., Neznanov N.G. Depressivnoe rasstroistvо. — M. GEHOTAR–MediA, Moskvа. — 2018. — 112s. (Seriya «Biblioteka vracha-spetsialista»)] (In Russ.)

3. Незнанов Н.Г., Мазо Г.Э., Рукавишников Г.В. Влияние антидепрессантов на когнитивные функции пациентов с депрессивным расстройством. Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева. 2015; 3:75–82. [Neznanov N.G., Mazo G.E., Rukavishnikov G.V. Vliyanie antidepressantov na kognitivnye funktsii patsientov s depressivnym rasstroistvoм. // Obozrenie psikhiatrii i meditsinskoi psikhologii imeni V.M. BekhterevA. 2015; 3:75-82] (InRuss.)

4. Al-Harbi KS. Treatment-resistant depression: therapeutic trends, challenges, and future directions. Patient Prefer. Adherence. 2012; 6:369–388. DOI: 10.2147/PPA.S29716

5. Ameli R, Luckenbaugh DA., Gould NF., Kathleen Holmes M, Lally N, Ballard ED, & ZarateCA. SHAPS-C: The Snaith-Hamilton pleasure scale modified for clinician administration. PeerJ. 2014; 1:e429. https://doi.org/10.7717/peerj.429

Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3