Effectiveness of neurotropic therapy in the treatment of non-psychotic mental disorders in patients who have suffered a cerebral stroke

Abstract

The purpose of the study: to clarify the prevalence of non-psychotic mental disorders in the population of patients suffered a cerebral stroke, and to assess the potential use of neurotropic drugs for the correction of certain types of psychopathological syndromes. Materials and methods: 180 patients were examined in the recovery period of brain stroke (the average duration of stroke was 20.7±6.6 months): 78 men and 102 women aged 39 to 90 years (the average age was 64.8±11.2). All patients underwent neuroimaging, experimental psychological research and a psychiatrist’s examination. Results: as a result of the survey, almost all patients in the recovery period of a brain stroke (90.5%) were found non-psychotic mental disorders with a predominance of psychoasthenic syndrome and mnestic-intellectual disorders that develop because of the predomimamt lesion of the brain frontal lobes. As a result of isolated neurotropic therapy, several therapeutic tasks were solved: treatment of focal neurological deficit, reduction of asthenia and the severity of mnestico-intellectual disorders, reduced drug load on the patient. Conclusion: the majority of patients in the recovery period of stroke have various psychopathological disorders, but due to somatic burden can not always receive psychotropic therapy. In this case, it is important to use new approaches to the correction of psychopathological disorders. The use of isolated neurotropic therapy has shown high efficiency in correcting the psychopathological component of stroke, which allows solving several rehabilitation tasks. Research on various aspects of post-stroke mental disorders can help identify additional opportunities for personalized and safe treatment of patients who have suffered acute stroke.