Lithium toxicity following Roux-en-Y gastric bypass: Mini review and illustrative case

Author:

Ayub Shahana1ORCID,Saboor Sundas2ORCID,Usmani SadiaORCID,Javed Sana3ORCID,Tonpouwo Gauvain Kankeu4ORCID,Ahmed Saeed5ORCID

Affiliation:

1. 1 Psychiatrist, Cornerstone Family Health, Newburgh, New York

2. 2 Physician, Khyber Medical College, Peshawar, Khyber Pakhtunkhwa, Pakistan

3. 4 Physician, Nishtar Medical University, Multan, Punjab, Pakistan

4. 5 Physician, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo

5. 6 Addiction Psychiatrist, Rutland Regional Medical Center, Rutland, Vermont

Abstract

Abstract Lithium is among the mainstays of treatment for bipolar disorder. Bariatric surgery can considerably change the oral bioavailability of drugs, particularly lithium. In this review, a 36-year-old male patient is described, who presented with lithium toxicity, including neurologic and gastric symptoms after undergoing Roux-en-Y gastric bypass. The mechanism of lithium toxicity is discussed; recommendations for clinicians regarding lithium use in postsurgical patients are provided; and previous case reports of lithium toxicity post-gastric bypass surgery are analyzed. Awareness and education of lithium absorption changes postbariatric surgery is essential for optimal patient care. Close clinical and drug concentration level monitoring is warranted.

Publisher

College of Psychiatric and Neurologic Pharmacists (CPNP)

Subject

Pharmacology (medical),Neurology (clinical),General Pharmacology, Toxicology and Pharmaceutics,Neuropsychology and Physiological Psychology

Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Lithium Toxicity;The Lithium Handbook;2023-11-09

2. Management of Routine Lithium Related Adverse Effects;The Lithium Handbook;2023-11-09

3. Clinical Pharmacokinetics;The Lithium Handbook;2023-11-09

4. Consultation-Liaison Case Conference: Psychiatric Care of Patients Who Undergo Bariatric Surgery;Journal of the Academy of Consultation-Liaison Psychiatry;2023-05

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