Emerging therapies of hemangioblastomas

Author:

Sanghadia Chaitanya1ORCID,Martinez Melanie E.2ORCID,McNulty Marisa3ORCID,Russ Eric3ORCID,Woolridge Maxwell3,Cao Dat Thanh3ORCID,Micunovic Marko3ORCID,Roberts Jeffery4,Perez Juan3,Lucke-Wold Brandon3ORCID

Affiliation:

1. Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona 85721, USA

2. Department of Neuroscience, University of Florida, Gainesville, Florida 32611, USA

3. Department of Neurosurgery, University of Florida, Gainesville, Florida 32611, USA

4. Department of Otolaryngology, University of Florida, Gainesville, Florida 32611, USA

Abstract

Hemangioblastoma are benign, vascularized cranial tumors caused by autosomal dominant inherited von Hippel-Lindau disease or can appear sporadically. This review will investigate current and emerging treatments for cerebral tumors. It will focus on the current and, more importantly, developing hemangioblastoma treatments. Surgical resectioning and radiotherapy are effective treatment options for cerebral tumors, whereas chemotherapies are not commonly used due to their limited ability to penetrate the blood-brain barrier. Recent chemotherapies have shown promise, but further research is needed to determine the efficacy as a treatment for hemangioblastomas. New advances in brachytherapy and immunotherapy are considered promising treatment options for hemangioblastoma. This review aims to offer valuable insights into the latest developments in hemangioblastoma treatments.

Publisher

Open Exploration Publishing

Subject

General Medicine,General Earth and Planetary Sciences,General Environmental Science,General Medicine,Ocean Engineering,General Medicine,General Medicine,General Medicine,General Medicine,General Earth and Planetary Sciences,General Environmental Science,General Medicine

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