Glucose metabolism reprogramming promotes immune escape of hepatocellular carcinoma cells-Reference-Cited by-同舟云学术

Glucose metabolism reprogramming promotes immune escape of hepatocellular carcinoma cells

Published:2023-06-30 Issue: Volume: Page:519-536
ISSN:2692-3114
Container-title:Exploration of Targeted Anti-tumor Therapy
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Author:

Zhang Qiuyue¹,Liu Jinchen¹,Lin Haifeng²,Lin Bo¹^ORCID,Zhu Mingyue¹^ORCID,Li Mengsen³^ORCID

Affiliation:

1. Hainan Provincial Key Laboratory of Carcinogenesis and Intervention, Hainan Medical College, Haikou 571199, Hainan Province, China

2. Department of Medical Oncology, Second Affiliated Hospital, Hainan Medical College, Haikou 570216, Hainan Province, China

3. Hainan Provincial Key Laboratory of Carcinogenesis and Intervention, Hainan Medical College, Haikou 571199, Hainan Province, China; Department of Medical Oncology, Second Affiliated Hospital, Hainan Medical College, Haikou 570216, Hainan Province, China; Institution of Tumor, Hainan Medical College, Haikou 570102, Hainan Province, China

Abstract

Hepatocellular carcinoma (HCC) is a complex process that plays an important role in its progression. Abnormal glucose metabolism in HCC cells can meet the nutrients required for the occurrence and development of liver cancer, better adapt to changes in the surrounding microenvironment, and escape the attack of the immune system on the tumor. There is a close relationship between reprogramming of glucose metabolism and immune escape. This article reviews the current status and progress of glucose metabolism reprogramming in promoting immune escape in liver cancer, aiming to provide new strategies for clinical immunotherapy of liver cancer.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Hainan Province

Publisher

Open Exploration Publishing

Subject

Cancer Research,Oncology

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