Affiliation:
1. Department of Organic Chemistry, Faculty of Sciences, University of Malaga, 29071 Malaga, Spain
Abstract
Bacterial infections constitute one of the major cases of primary medical incidences worldwide. Historically, the fight against bacterial infections in humans has been an ongoing battle, due to the ability of bacteria to adapt and to survive. Indeed, bacteria have developed various mechanisms of resistance against several therapeutic agents. Consequently, the scientific community is always interested in search of new therapeutic agents, which are able to efficiently kill resistant-bacterial strains. This article covers the most recent antibacterial molecules approved by the Food and Drugs Administration (FDA) and European Medicines Agency (EMA) from 2012 to 2022 and intends to focus on synthetic derivatives to give a pedagogical view, with the goal of highlighting the importance of organic synthesis to obtain greater efficacy. A focus will be made on studies describing the structure and activity of the organic molecules and their interactions with their respective biological targets.
Publisher
Open Exploration Publishing
Subject
Information Systems and Management,Information Systems,Software,General Engineering,General Energy,General Medicine,General Medicine,General Medicine,Geriatrics and Gerontology,General Materials Science,General Medicine,Anesthesiology and Pain Medicine
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