Natural compounds from medicinal plants against COVID-19-Reference-Cited by-同舟云学术

Natural compounds from medicinal plants against COVID-19

Published:2023-08-28 Issue: Volume: Page:253-275
ISSN:
Container-title:Exploration of Drug Science
language:
Short-container-title:Explor Drug Sci

Author:

Kolodnitsky Anton¹^ORCID,Ionov Nikita²^ORCID,Gravel Irina³^ORCID,Poroikov Vladimir²^ORCID

Affiliation:

1. Laboratory of Structure-Function Based Drug Design, Institute of Biomedical Chemistry, 119121 Moscow, Russia; Department of Pharmaceutical Natural Science, Institute of Pharmacy Named after A.P. Nelyubin, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia

2. Laboratory of Structure-Function Based Drug Design, Institute of Biomedical Chemistry, 119121 Moscow, Russia

3. Department of Pharmaceutical Natural Science, Institute of Pharmacy Named after A.P. Nelyubin, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia

Abstract

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), known to cause the coronavirus disease 2019 (COVID-19), was declared a pandemic in early 2020. During the past time, several infections control methods have been developed. Nevertheless, all of them have certain limitations: uncertainty in duration, limited efficacy of vaccines, and lack of effective drugs for COVID-19 treatment. So, the issue of creating drugs for symptomatic and etiotropic therapy is still relevant. This review summarizes the current knowledge of using natural compounds as anti-SARS-CoV-2 agents by analysing the results of in vitro studies and completed clinical trials (CTs). Also, this work highlighted the most active molecules and discussed the possibility of using some compounds in clinical practice.

Publisher

Open Exploration Publishing

Subject

General Medicine,General Medicine,General Medicine,General Earth and Planetary Sciences,General Environmental Science,Management Science and Operations Research,Mechanical Engineering,Energy Engineering and Power Technology,Computer Networks and Communications,Hardware and Architecture,Software,Immunology and Allergy,Applied Mathematics,General Mathematics,General Medicine,General Medicine,General Chemistry

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