Effect of dietary changes on intestinal absorption of L-methionine and L-methionyl-L-methionine in the rat

Author:

Lis Maria T.,Crampton R. F.,Matthews D. M.

Abstract

1. The absorption rates of L-methionine and L-methionyl-L-methionine (dimethionine) from the upper jejunum and lower ileum of the rat were studied in vivo after different dietary treatments. Rates were expressed per unit gut length and per unit gut weight; the former was considered to be the more satisfactory under the different dietary conditions.2. The dietary treatments were either short-term (10 d) or long-term (40–84 d).3. The rate of absorption of methionine increased in the jejunum after a restricted dietary intake, a high-protein diet or a high-methionine diet, but decreased after long-term protein deprivation. Short-term dietary restriction had a similar effect on methionine absorption in jejunum and ileum, though less pronounced in the latter. The rate of absorption of dimethionine was less influenced by dietary changes than that of methionine.4. Under all conditions studied, the absorption rate of methionine was greater when presented as the dipeptide than when presented as the equivalent amount of free amino acid. This confirms that dimethionine is taken up intact from the intestinal lumen, and it seems likely that there are different mechanisms of mucosal uptake for methionine and its dipeptide.

Publisher

Cambridge University Press (CUP)

Subject

Nutrition and Dietetics,Medicine (miscellaneous)

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3