Author:
Garrow J. S.,Hawes Susan F.
Abstract
1. The increase in metabolic rate which occurs after ingestion of protein (the so-called ‘specific dynamic action’) has been attributed to the energy requirements for urea synthesis and amino acid degradation.2. We have tested, in normal adult subjects, the effect of meals which increase or decrease the rate of urea production, and our results do not substantiate this hypothesis.3. The difficulties of accurate measurement of resting metabolic rate are discussed.4. The term ‘specific dynamic action’ is inappropriate since the effect is not specific. We believe that it may prove to be a reflection of protein synthesis rather than of protein catabolism.
Publisher
Cambridge University Press (CUP)
Subject
Nutrition and Dietetics,Medicine (miscellaneous)
Cited by
87 articles.
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1. Postprandial thermogenesis in Bothrops moojeni (Serpentes: Viperidae);Journal of Venomous Animals and Toxins including Tropical Diseases;2011
2. Specific dynamic action: A century of investigation;Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology;2006-08
3. The Effect of Meal Composition on Specific Dynamic Action in Burmese Pythons (Python molurus);Physiological and Biochemical Zoology;2005-03
4. Daily delivery of dietary nitrogen to the periphery is stable in rats adapted to increased protein intake;American Journal of Physiology-Endocrinology and Metabolism;2001-10-01
5. Nutrient induced thermogenesis;Baillière's Clinical Endocrinology and Metabolism;1997-12