Antimicrobial Activity of Native Chitosan, Degraded Chitosan, and O-Carboxymethylated Chitosan

Author:

KIM KYUNG W.1,THOMAS R. L.1,LEE CHAN2,PARK HYUN J.13

Affiliation:

1. 1Department of Packaging Science, Clemson University, Clemson, South Carolina, 29634-0370, USA

2. 2Department of Food Science and Technology, Chung-Ang University, Ansung, Korea

3. 3Graduate School of Biotechnology, Korea University, Seoul 136-701, Korea

Abstract

The antimicrobial activity of native chitosan was compared to that of lipase-degradedchitosan. The effects of O-carboxymethylated (O-CM) substitution on native (molecular weight, 120; degree of deacetylation, 84.71%) and lipase-degraded chitosans were also investigated. The antimicrobial activity of native chitosan was more extensive than that of lipase-degraded chitosan; however, lipase-degraded chitosan was still highly effective and more water-soluble. O-CM chitosan derived from degraded chitosan was more effective than O-CM chitosan derived from native chitosan. O-CM substitution enhanced lipase-degraded chitosan's antimicrobial activity without reducing its solubility.

Publisher

International Association for Food Protection

Subject

Microbiology,Food Science

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