Abstract
ABSTRACT
Aim: To investigate some clinical and paraclinical characteristics and pregnant outcomes of pregnant women with COVID-19 at COVID-19 Research and Treatment Central of Hue.
Methods: This retrospective observational study included all identified COVID-19- positive pregnant women admitted to the Hue Central Hospital – Branch 2 at labour from September 2021 to March 2022. Maternity and newborns were followed until discharge from the hospital.
Results: Eighty-three pregnant women were positive for COVID-19. There were 32.5 % asymptomatic cases, 43.4 % had mild symptoms, while 21,1 % had more severe forms of the disease. The main follow-up morbidities were high BMI 24,1 %, anaemia 22.9 %, hypertensive disorders 4.8% and diabetes 2.4 %. The rate of premature births was 12.3%. There are 3/83 pregnant women with twins (3.6 %). Caesarean section was done for 63.9 % of women while 36.1 % delivered vaginally. Previous caesarean section (30.2%) was the most common indication for operative completion of labour. Eighty-five (98.8%) live babies were born, of which 11 (13.3%) were admitted to the neonatal intensive care unit. One baby (1.2%) died shortly after birth due to multiple malformations. Two infants (2.3 %) had a positive PCR test for COVID-19. Conclusion: Most pregnant women infected with COVID-19 are asymptomatic and mild. Almost pregnant women recovered well after giving birth, but 2 mothers died due to severe development of COVID-19 (their children’s lives were saved). 11 babies needed care in the NICU, one baby (1.2%) died soon after birth due to multiple malformations/prematurity. Two infants (2.3 %) had a positive PCR test for COVID-19.
Reference33 articles.
1. 1. Bộ Y tế. Quyết định về việc ban hành Hướng dẫn tạm thời Dự phòng và xử trí COVID-19 do chủng vi rút Sars-CoV -2 ở phụ nữ mang thai và trẻ sơ sinh, (Ban hành kèm theo Quyết định số 3982 /QĐ-BYT ngày 18 tháng 08 năm 2021).
2. 2. Zoumpourlis V, Maria G, Emmanouil R et al. The COVID‐19 pandemic as a scientific and social challenge in the 21st century. Molecular Medicine REPORTS. 2019. 22:3035-3048.
3. 3. Vale AJM, Fernandes ACL, Guzen FP et al. Susceptibility to COVID-19 in pregnancy, labor, and postpartum period: immune system, vertical transmission, and breastfeeding. Front Glob Womens Health. 2021. 2:602572.
4. 4. Miranda JD, Michael W, Alissa O et al. Characteristics and Maternal and Birth Outcomes of Hospitalized Pregnant Women with Laboratory-Confirmed COVID-19 COVIDNET, 13 States, March 1-August 22, 2020, MMWR. 2020. 69(38):63-70.
5. 5. Oscar MP, Pilar PR, Marta MH. The association between SARS-CoV-2 infection and preterm delivery: a prospective study with a multivariable analysis. BMC Pregnancy Childbirth. 2021. 21:273.