Is the Occurrence of Gestational Diabetes Mellitus in Pregnancies Higher Following In Vitro Fertilization Treatment? Why? A Retrospective Cohort Study

Author:

AYPAR AKBAĞ Nuran Nur1ORCID,ALUŞ TOKAT Merlinda2ORCID,FATA Sevcan2ORCID,ÜNSAL AVDAL Elif3ORCID,OKYAY Emre4ORCID,DOĞAN Ömer Erbil4ORCID

Affiliation:

1. KARAMANOĞLU MEHMETBEY ÜNİVERSİTESİ

2. DOKUZ EYLUL UNIVERSITY, FACULTY OF NURSING

3. IZMIR KATIP CELEBI UNIVERSITY, FACULTY OF HEALTH SCIENCES

4. DOKUZ EYLUL UNIVERSITY, SCHOOL OF MEDICINE

Abstract

Purpose: This study aim to determine the occurrence of gestational diabetes mellitus (GDM) in pregnancies after IVF treatment and to evaluate the factors that reduce this risk. Methods: This retrospective cohort study was conducted using the medical records of pregnant women who conceived following IVF at the in-vitro fertilization center between 2002–2019. The data were obtained from medical records and phone interviews. Univariate and multivariate logistic regression analyses were performed. Results: The incidence of GDM was found to be 16.7%. The regression model indicated that the risk of GDM was 4.57 times higher in the age group 36–40 at conception during the IVF cycle than the age group 31–35 (95% CI = 1.18–17.73, p = .028). Furthermore, women who conceived after the second IVF trial had a risk of GDM 3.464 times higher than those that conceived after their first IVF trial (95% CI = 1.07–11.23, p= .038). Conclusion: As age and number of IVF trials increase in infertile women, the risk of GDM increases after IVF treatment.

Publisher

Dokuz Eyul Universitesi Saglik Bilimleri Enstitusu

Subject

General Medicine

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