Evaluation of Socio-demographic Factors and Comorbidities in Adult Hemophilia Patients

Abstract

Purpose: The association between socio-demographic factors and hemophilia status and the prevalence of comorbidities were evaluated. Material and Methods: Patients with hemophilia A (n=111) and B (n=24) who were filled a questionnaire form about their sociodemographic factors were included in our study. Factor and inhibitor levels, comorbidities, factor replacement therapies, hemophilic arthropathy, viral status and annual bleeding episodes were recorded. Results: Median age was 39 years in 135 hemophilia patients and 63.1 % of all the patients had severe hemophilia which was significantly higher among hemophilia A patients (p=0.002). Most of the patients (74.8%) were treated with prophylactic factor replacement therapy. Inhibitor status was positive in 8.9% of all patients. Unemployment rate was found 33.3%. Annual bleeding episodes were higher in patients who had a job. Most of the patients (60 %) were graduated from at least high school. The prevalence of cardiovascular disease, hypertension, diabetes mellitus and obesity were 6.7%; 17.8%, 13.3%, 11.9% respectively. Although there is no association between the obesity and annual bleeding episodes, right ankle was the most affected joint in overweight/obese patients. Conclusion: Age-related comorbidities and the relation of hemophilia status and social life are needed to be more investigated.