In older patients with AF and frailty, switching from VKA to NOAC therapy increased a composite of major or CRNM bleeding at 12 mo
Author:
Affiliation:
1. Icahn Mount Sinai School of Medicine, New York, NY, USA (A.D.)
Publisher
American College of Physicians
Link
https://www.acpjournals.org/doi/pdf/10.7326/J24-0024
Reference3 articles.
1. Ruff CT, Giugliano RP, Braunwald E, et al. Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials. Lancet. 2014;383:955-962. [PMID: 24315724]
2. He L, He R, Huang J, et al. Impact of frailty on all-cause mortality and major bleeding in patients with atrial fibrillation: a meta-analysis. Ageing Res Rev. 2022;73:101527. [PMID: 34839042]
3. Haas S, Ten Cate H, Accetta G, et al; GARFIELD-AF Investigators. Quality of vitamin K antagonist control and 1-year outcomes in patients with atrial fibrillation: a global perspective from the GARFIELD-AF registry. PLoS One. 2016;11:e0164076. [PMID: 27792741]
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