In Enterobacterales bacteremia, antipseudomonal β-lactam de-escalation was noninferior to continuation for clinical cure at 3 to 5 d
Author:
Affiliation:
1. Houston Methodist Hospital, Houston, Texas, USA (K.O., E.M.)
Publisher
American College of Physicians
Link
https://www.acpjournals.org/doi/pdf/10.7326/J24-0030
Reference2 articles.
1. Weiss E, Zahar JR, Lesprit P, et al; De-escalation Study Group. Elaboration of a consensual definition of de-escalation allowing a ranking of β-lactams. Clin Microbiol Infect. 2015;21:649.e1-649.e10. [PMID: 25882363]
2. Leone M, Bechis C, Baumstarck K, et al; AZUREA Network Investigators. De-escalation versus continuation of empirical antimicrobial treatment in severe sepsis: a multicenter non-blinded randomized noninferiority trial. Intensive Care Med. 2014;40:1399-1408. [PMID: 25091790]
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