After PCI in older adults, DAPT for 3 vs. 6 or 12 mo reduces bleeding without increasing NACE or MACE
Author:
Affiliation:
1. University of Toronto, Toronto, Ontario, Canada (C.C.)
2. St. Michael’s Hospital and University of Toronto, Toronto, Ontario, Canada (A.T.Y.)
Publisher
American College of Physicians
Link
https://www.acpjournals.org/doi/pdf/10.7326/ANNALS-24-00961-JC
Reference5 articles.
1. Primary Panel; Bainey KR, Marquis-Gravel G, Belley-Côté E, et al. Canadian Cardiovascular Society/Canadian Association of Interventional Cardiology 2023 focused update of the guidelines for the use of antiplatelet therapy. Can J Cardiol. 2024;40:160-181. [PMID: 38104631]
2. Andò G, De Santis GA, Greco A, et al. P2Y12 inhibitor or aspirin following dual antiplatelet therapy after percutaneous coronary intervention: a network meta-analysis. JACC Cardiovasc Interv. 2022;15:2239-2249. [PMID: 36423966]
3. Hong SJ, Lee SJ, Suh Y, et al; T-PASS (Ticagrelor Monotherapy in Patients Treated With New-Generation Drug-Eluting Stents for Acute Coronary Syndrome) Investigators. Stopping aspirin within 1 month after stenting for ticagrelor monotherapy in acute coronary syndrome: the T-PASS randomized noninferiority trial. Circulation. 2024;149:562-573. [PMID: 37878786]
4. Kim BK, Hong SJ, Cho YH, et al; TICO Investigators. Effect of ticagrelor monotherapy vs ticagrelor with aspirin on major bleeding and cardiovascular events in patients with acute coronary syndrome: the TICO randomized clinical trial. JAMA. 2020;323:2407-2416. [PMID: 32543684]
5. Lee SY, Hong MK, Palmerini T, et al. Short-term versus long-term dual antiplatelet therapy after drug-eluting stent implantation in elderly patients: a meta-analysis of individual participant data from 6 randomized trials. JACC Cardiovasc Interv. 2018:11:435-443. [PMID: 29454730]
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