In adults with COVID-19 and severe hypoxemia, lower vs. higher oxygenation targets increased days alive without life support
Author:
Affiliation:
1. University of California San Diego <>, La Jolla, California, USA (D.A.S.)
2. University of Nebraska Medical Center, Omaha, Nebraska, USA (A.C.K.)
Publisher
American College of Physicians
Link
https://www.acpjournals.org/doi/pdf/10.7326/ANNALS-24-00558-JC
Reference5 articles.
1. Hafner S, Beloncle F, Koch A, et al. Hyperoxia in intensive care, emergency, and peri-operative medicine: Dr. Jekyll or Mr. Hyde? A 2015 update. Ann Intensive Care. 2015;5:42. [PMID: 26585328]
2. Chu DK, Kim LH, Young PJ, et al. Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis. Lancet. 2018;391:1693-1705. [PMID: 29726345]
3. Barrot L, Asfar P, Mauny F, et al; LOCO2 Investigators and REVA Research Network. Liberal or conservative oxygen therapy for acute respiratory distress syndrome. N Engl J Med. 2020;382:999-1008. [PMID: 32160661]
4. Angus DC. Oxygen therapy for the critically ill [Editorial]. N Engl J Med. 2020;382:1054-1056. [PMID: 32160668]
5. Singer M, Young PJ, Laffey JG, et al. Dangers of hyperoxia. Crit Care. 2021;25:440. [PMID: 34924022]
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