A survey of AFM1 contamination in row cow milk produced in region of Kumanovo-Reference-Cited by-同舟云学术

A survey of AFM1 contamination in row cow milk produced in region of Kumanovo

Published:2019 Issue:2 Volume:65 Page:49-55
ISSN:1857-8969
Container-title:Macedonian Pharmaceutical Bulletin
language:en
Short-container-title:Maced. Pharm. Bull.

Author:

Furunovikj-Dimitrijevski Iva¹,Angelova Suzana²,Shutevska Kristina³,Kadifkova Panovska Tatjana³

Affiliation:

1. PZU Apteka Ilinden, Done Bozinov 18, 1300 Kumanovo, Republic of North Macedonia

2. PHI Center for Public Health Kumanovo, October 11th b.b, 1300 Kumanovo, Republic of North Macedonia

3. Institute of Applied Biochemistry, Faculty of Pharmacy, Ss. Cyril and Methodius University, Mother Theresa 47, 1000 Skopje, Republic of North Macedonia

Abstract

Aflatoxins (AFs) are type of mycotoxins produced by certain Aspergillus species. In the livers of cows, the aflatoxin В1 (AFB1) ingested with contaminated food is metabolized in carcinogenic aflatoxin М1 (AFM1) which is then excreted in the milk and poses a serious risk to the health of the consumers. In January of 2019, twenty five (25) samples of milk were collected from local farms in the surrounding area of Kumanovo, Republic of North Macedonia. The samples were analysed in the Centre for Public Health, Kumanovo. A method MKC EN ISO 14501:2007 for analysis of AFM1 by HPLC with fluorescence detection was applied. This method is selective, precise and applicative. The final analytical result has shown AFM1 below the LOD in any of the analyzed samples. Due to the well-known fact that AFM1 is toxic, i.e. carcinogenic and the fact that milk is widely used as staple food, continuous development as well as introduction of new, more sensitive methods for detection of AFM1 are required. Keywords: Aflatoxin M1, HPLC-FLD, milk

Publisher

Macedonian Pharmaceutical Association

Subject

General Medicine

Link

http://bulletin.mfd.org.mk/volumes/Volume%2065_2/65_2_006.pdf

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