Fast, simple HPLC method for determination of Spironolactone related compounds

Author:

Piponski Marjan1,Slaveska Spirevska Irena1,Bakovska Stoimenova Tanja1,Grncharoska Kristina1,Miloshevska Martina1,Prculovska Milena1,Bogoevska Marika1,Stefov Stefan1

Affiliation:

1. Replek Farm Ltd., Kozle 188, 1000, Skopje, N. Macedonia

Publisher

Macedonian Pharmaceutical Association

Subject

General Engineering,Energy Engineering and Power Technology

Reference5 articles.

1. British Pharmacopoeia, 2022. British Pharmacopoeia Commission - The Stationery Office: London.

2. European Pharmacopoeia, 11th ed., 2023. European Directorate for the Quality of Medicines & Healthcare – Council of Europe: Strasbourg.

3. Hegazy, M.A., Metwaly, F.H., Abdelkawy, M., Abdelwahab, N.S., 2011. Validated chromatographic methods for determination of hydrochlorothiazide and spironolactone in pharmaceutical formulation in presence of impurities and degradants. Journal of chromatographic science, 49(2), 129-135.

4. International Conference on Harmonization, 2005. Validation of analytical procedures: Text and methodology Q2(R1). ICH, Geneva, Switzerland.

5. The United States Pharmacopeia / The National Formulary (USP 43-NF 38),2020. The United States Pharmacopeia Convention: Rockville.

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