Hydrophilic polymer based oral formulations studied by NMR relaxometry and UTE MRI - towards polymer mobilization and erosion assessment
Author:
Affiliation:
1. Institute of Technology, The Pedagogical University of Kraków, Podchorążych 2, 30-084 Kraków, Poland
2. Department of Drug Technology and Pharmaceutical Biotechnology, Medical University of Warsaw, Banacha 1, 02-097 Warszawa, Poland
Publisher
Macedonian Pharmaceutical Association
Subject
General Engineering,Energy Engineering and Power Technology
Link
https://bulletin.mfd.org.mk/volumes/Volume%2069_3/69_3_107.pdf
Reference6 articles.
1. Baran, E., Birczyński, A., Dorożyński, P. & Kulinowski, P., 2023. Low-field time-domain NMR relaxometry for studying polymer hydration and mobilization in sodium alginate matrix tablets. Carbohydrate Polymers, 299, 120215.
2. Caccavo, D., Cascone, S., Lamberti, G., Barba, A.A. & Larsson, A., 2016. Swellable Hydrogel-based Systems for Controlled Drug Delivery. In S. Ali Demir (ed.) Smart Drug Delivery System. Rijeka: IntechOpen, 237-303.
3. Dahlberg, C., Fureby, A., Schuleit, M., Dvinskikh, S.V. & Furo, I., 2007. Polymer mobilization and drug release during tablet swelling. A H-1 NMR and NMR microimaging study. Journal of Controlled Release, 122, 199-205.
4. Dahlberg, C., Dvinskikh, S.V., Schuleit, M. & Furo, I., 2011. Polymer Swelling, Drug Mobilization and Drug Recrystallization in Hydrating Solid Dispersion Tablets Studied by Multinuclear NMR Microimaging and Spectroscopy. Molecular Pharmaceutics, 8, 1247-1256.
5. Juszczyk, E., Kulinowski, P., Baran, E., Birczyński, A., Klaja, J., Majda, D., Garcia-Montoya, E., Węglarz, W.P. & Dorożyński, P., 2021a. Hydration Patterns in Sodium Alginate Polymeric Matrix Tablets-The Result of Drug Substance Incorporation. Materials (Basel, Switzerland), 14, 6531.
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