COMPARISON OF DIFFERENT METHODS OF ANTI-HLA ANTIBODIES DETECTION IN DIAGNOSIS OF ANTIBODY-MEDIATED RENAL ALLOGRAFT REJECTION

Author:

Ivanova E. S.1,Stolyarevich E. S.2,Gichkun O. E.3,Bogdanova N. B.3,Baranova F. S.4,Artyukhina L. Yu.4,Tomilina N. A.2

Affiliation:

1. V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow, Moscow; Moscow City Nephrology Center, Moscow City Hospital N 52, Moscow

2. V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow, Moscow; A.I. Evdokimov Moscow State University of Medicine and Dentistry, Moscow

3. V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow, Moscow

4. Moscow City Nephrology Center, Moscow City Hospital N 52, Moscow

Publisher

V.I. Shimakov Federal Research Center of Transplantology and Artificial Organs

Subject

Transplantation,Immunology and Allergy

Reference42 articles.

1. Gourishankar S, Leduc R, Connett J et al. Pathological and clinical characterization of the «troubled transplant»: data from the DeKAF study. Am. J. Transplant. 2010 Feb; 10 (2): 324–330.

2. Gaston RS, Cecka JM, Kasiske BL et al. Evidence for antibody-mediated injury as a major determinant of late kidney allograft failure. Transplantation. 2010 Jul 15; 90 (1): 68–74.

3. Stolyarevich ES, Artyukhina LYu, Kim IG, Kurenkova LG, Tomilina NA. Morfologicheskie osobennosti pozdnego ottorzheniya transplantirovannoi pochki i ikh vliyanie na techenie i prognoz nefropatii. Nefrologiya i dializ. 2012; 4: 242–252. Stolyarevich ES, Artyukhina LYu, Kim IG, Kurenkova LG, Tomilina NA. Morfologicheskie osobennosti pozdnego ottorzheniya transplantirovannoy pochki i ikh vliyanie na techenie i prognoz nefropatii. Nefrologiya i dializ. 2012; 4: 242– 252.

4. Mauiyyedi S, Pelle PD, Saidman S et al. Chronic humoral rejection: Identifi cation of antibody-mediated chronic allograft rejection by C4d deposits in peritubular capillaries. J. Am. Soc. Nephrol. 2001; 12: 574–582.

5. Regele H, Bohmig GA, Habicht A et al. Capillary deposition of complement split product C4d in renal allografts is associated with basement membrane injury in peritubular and glomerular capillaries: A contribution of humoral immunity to chronic allograft rejection. J. Am. Soc. Nephrol. 2002; 13: 2371–2380.

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1. The mechanism of humoral immune response to allogeneic organ transplantation;Russian Journal of Transplantology and Artificial Organs;2017-06-23

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