Effect of syphaciosis on biochemical and clinical blood parameters of laboratory rats

Author:

Emelyanova N. B.1ORCID,Kurnosova O. P.1ORCID

Affiliation:

1. All-Russian Scientific Research Institute for Fundamental and Applied Parasitology of Animals and Plant – a branch of the Federal State Budget Scientific Institution “Federal Scientific Centre VIEV”

Abstract

The purpose of the research is to study the effect of syphaciosis on biochemical and clinical blood parameters of outbred rats.Materials and methods. Outbred male rats weighing 180–200 g were examined for helminth eggs by coproovoscopy and a Scotch tape test using a microscope Micromed 1 ver. 2-20. A biochemical blood assay was conducted on a Beckman Coulter DxC 700AU analyzer (USA), and a haematology test panel was made on a PCE 90-Vet analyzer (USA). Fenbendazole was used for preventive dehelminthization. Statistical processing was performed using the software Studet200.Results and discussion. The study results on biochemistry and hematology of the outbred rats’ blood showed a significant decrease in LDH levels and an increase in hematocrit in the animals infected with Syphacia spp.

Publisher

Institute of Fundamental and Applied Parasitology of Animals and Plants

Subject

Insect Science,Ecology,Ecology, Evolution, Behavior and Systematics

Reference16 articles.

1. Abdrashitova E. Kh., Zaitsev T. I., Braude N. A., Komarovskaya T. P., Novikova R. F., Poleshchuk V. D., Kuchding E., Knopke K. et al. Quality categories of laboratory rodents for health and their standardization. «Laboratornoye zhivotnovodstvo dlya medikobiologicheskikh i biotekhnologicheskikh issledovaniy»: tezisy konferentsii = "Laboratory animal husbandry for biomedical and biotechnological research": the Conference abstracts. М., 1990; 58-65. (In Russ.)

2. Aksenov V. I. General objectives for quality control of laboratory animals’ health. «Aktual'nyye voprosy standartizatsii laboratornykh zhivotnykh dlya medikobiologicheskikh issledovaniy»: tezisy Vsesoyuznoy konferentsii = "Current standardization issues of laboratory animals for biomedical research": the AllUnion Conference abstracts. М., 1988; 1: 3-5. (In Russ.)

3. Bolotskikh L. A., Beskova T. B., Galakhova T. V., Zaitsev T. I. Gnotobiotic method to obtain and keep nuclear stock of Specific Pathogen-Free laboratory animals. «Laboratornoye zhivotnovodstvo dlya medikobiologicheskikh i biotekhnologicheskikh issledovaniy»: tezisy konferentsii = "Laboratory animal husbandry for biomedical and biotechnological research": the Conference abstracts. М., 1990; 46. (In Russ.)

4. Grishina E. A., Erovichenkov A. A. Biochemical rationale for the use of complex therapy in the acute experimental helminthiasis phase in animals. Journal of Infectiology. St. Petersburg, 2017; 9 (3): 32-39. (In Russ.)

5. Dushkin V. A. Laboratory animal husbandry. Moscow: Rosselkhozizdat, 1980; 48. (In Russ.)

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