Simultaneous occurrence of primary mediastinal germ cell tumor and myelodysplastic syndrome: A case study and a concise review

Abstract

Primary mediastinal germ cell tumors are potentially aggressive neoplasms that are rarely associated with hematological malignancies in young men. The association between primary mediastinal germ cell tumors and hematological malignancies involves complex oncogenesis that has yet to be established, and these uncertainties are reflected in the unresponsiveness to the current therapeutic interventions, hence, leading to an unfavorable prognosis.