Gut Microbiota and Atrial Fibrillation: Pathogenesis, Mechanisms and Therapies-Reference-Cited by-同舟云学术

Gut Microbiota and Atrial Fibrillation: Pathogenesis, Mechanisms and Therapies

Published:2023-04-19 Issue: Volume:12 Page:
ISSN:2050-3377
Container-title:Arrhythmia & Electrophysiology Review
language:en
Short-container-title:Arrhythm Electrophysiol Rev

Author:

Al-Kaisey Ahmed M¹^ORCID,Figgett William²^ORCID,Hawson Joshua¹,Mackay Fabienne³^ORCID,Joseph Stephen A⁴,Kalman Jonathan M¹^ORCID

Affiliation:

1. Department of Cardiology, Royal Melbourne Hospital, Melbourne, Australia; Department of Medicine, University of Melbourne, Melbourne, Australia

2. Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia

3. QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia

4. Department of Cardiology, Royal Melbourne Hospital, Melbourne, Australia; Department of Cardiology, Western Health, Melbourne, Australia

Abstract

Over the past decade there has been an interest in understanding the role of gut microbiota in the pathogenesis of AF. A number of studies have linked the gut microbiota to the occurrence of traditional AF risk factors such as hypertension and obesity. However, it remains unclear whether gut dysbiosis has a direct effect on arrhythmogenesis in AF. This article describes the current understanding of the effect of gut dysbiosis and associated metabolites on AF. In addition, current therapeutic strategies and future directions are discussed.

Publisher

Radcliffe Media Media Ltd

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

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