Clinical Characteristics of De Novo Heart Failure and Acute Decompensated Chronic Heart Failure: Are They Distinctive Phenotypes That Contribute to Different Outcomes?-Reference-Cited by-同舟云学术

Clinical Characteristics of De Novo Heart Failure and Acute Decompensated Chronic Heart Failure: Are They Distinctive Phenotypes That Contribute to Different Outcomes?

Published:2021-02-19 Issue: Volume:7 Page:
ISSN:2057-7559
Container-title:Cardiac Failure Review
language:en
Short-container-title:Card Fail Rev

Author:

Raffaello Wilson Matthew¹^ORCID,Henrina Joshua²^ORCID,Huang Ian³^ORCID,Lim Michael Anthonius¹^ORCID,Suciadi Leonardo Paskah²^ORCID,Siswanto Bambang Budi⁴^ORCID,Pranata Raymond¹^ORCID

Affiliation:

1. Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia

2. Siloam Heart Institute, Siloam Hospitals Kebon Jeruk, Jakarta, Indonesia

3. Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin General Hospital, Bandung, Indonesia

4. Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia

Abstract

Heart failure is currently one of the leading causes of morbidity and mortality. Patients with heart failure often present with acute symptoms and may have a poor prognosis. Recent evidence shows differences in clinical characteristics and outcomes between de novo heart failure (DNHF) and acute decompensated chronic heart failure (ADCHF). Based on a better understanding of the distinct pathophysiology of these two conditions, new strategies may be considered to treat heart failure patients and improve outcomes. In this review, the authors elaborate distinctions regarding the clinical characteristics and outcomes of DNHF and ADCHF and their respective pathophysiology. Future clinical trials of therapies should address the potentially different phenotypes between DNHF and ADCHF if meaningful discoveries are to be made.

Publisher

Radcliffe Group Ltd

Subject

Cardiology and Cardiovascular Medicine

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