Age Considerations in the Invasive Management of Acute Coronary Syndromes

Author:

Oberoi Mansi1ORCID,Ainani Nitesh2,Abbott J Dawn3ORCID,Mamas Mamas A4ORCID,Velagapudi Poonam2ORCID

Affiliation:

1. Department of Internal Medicine, Sanford School of Medicine, University of South Dakota, Sioux Falls, SD

2. Division of Cardiovascular Medicine, University of Nebraska Medical Center, Omaha, NE

3. Department of Internal Medicine, Division of Cardiology, The Warren Alpert Medical School of Brown University, Providence, RI

4. Keele Cardiovascular Research Group, Institute of Applied Clinical Sciences, University of Keele, Stoke-on-Trent, UK

Abstract

The elderly constitute a major proportion of patients admitted with acute coronary syndrome (ACS) in the US. Due to pre-existing comorbidities, frailty, and increased risk of complications from medical and invasive therapies, management of ACS in the elderly population poses challenges. In patients with ST-elevation MI, urgent revascularization with primary percutaneous coronary intervention remains the standard of care irrespective of age. However, an early invasive approach in elderly patients with non-ST-elevation MI is based on individual evaluation of risks versus benefits. In this review, the authors discuss the unique characteristics of elderly patients presenting with ACS, specific geriatric conditions that need to be considered while making treatment decisions in these situations, and available evidence, current guidelines, and future directions for invasive management of elderly patients with ACS.

Publisher

Radcliffe Media Media Ltd

Subject

Cardiology and Cardiovascular Medicine

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