Author:
Chubb Henry,Whitaker John,Williams Steven E,Head Catherine E,Chung Natali AY,Wright Matthew J,O’Neill Mark, , , , , , ,
Abstract
Atrial septal defects (ASDs) are among the most common of congenital
heart defects and are frequently associated with atrial arrhythmias. Atrial
and ventricular geometrical remodelling secondary to the intracardiac shunt
promotes evolution of the electrical substrate, predisposing the patient to
atrial fibrillation and other arrhythmias. Closure of an ASD reduces the
immediate and long-term prevalence of atrial arrhythmias, but the evidence
suggests that patients remain at an increased long-term risk in comparison
with the normal population. The closure technique itself and its timing
impacts future arrhythmia risk profile while subsequent transseptal access
following surgical or device closure is complicated. Newer techniques
combined with increased experience will help to alleviate some of the
difficulties associated with optimal management of arrhythmias in these
patients.
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine
Cited by
39 articles.
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