Coronary Artery Disease in Patients with Severe Mental Illness

Author:

Tam To Brian1,Roy Roman1ORCID,Melikian Narbeh2,Gaughran Fiona P3ORCID,O’Gallagher Kevin2ORCID

Affiliation:

1. Cardiovascular Department, King’s College Hospital NHS Foundation Trust, London, UK

2. Cardiovascular Department, King’s College Hospital NHS Foundation Trust, London, UK; School of Cardiovascular and Metabolic Medicine & Sciences, British Heart Foundation Centre of Research Excellence, King’s College London, London, UK;

3. Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK; National Psychosis Service, South London and Maudsley NHS Foundation Trust, London, UK

Abstract

Severe mental illnesses (SMI), such as schizophrenia and bipolar disorder, are associated with a decrease in life expectancy of up to two decades compared with the general population, with cardiovascular disease as the leading cause of death. SMI is associated with increased cardiovascular risk profile and early onset of incident cardiovascular disease. Following an acute coronary syndrome, patients with SMI have a worse prognosis, but are less likely to receive invasive treatment. In this narrative review, the management of coronary artery disease in patients with SMI is discussed, and avenues for future research are highlighted.

Publisher

Radcliffe Media Media Ltd

Subject

Cardiology and Cardiovascular Medicine

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