After RIPCORD 2, FAME 3, FLOWER-MI and FUTURE: Has the Pressure Wire had its Day?

Author:

Modi Bhavik1ORCID,Dutta Subhabrata2,Collison Damien3ORCID,Lampadakis Ioannis4,Sen Sayan4

Affiliation:

1. Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, UK; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK

2. Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, UK

3. West of Scotland Regional Heart and Lung Centre, Golden Jubilee National Hospital, Glasgow, UK; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK

4. Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, UK

Abstract

Recent years have seen the publication of several high-profile, negative trials about pressure wires. This has coincided with a consistent increase in the ratio of angioplasty for acute coronary syndromes versus percutaneous coronary intervention in stable coronary artery disease, a greater use of intracoronary imaging during percutaneous coronary intervention and the continued evolution of computational fluid dynamics-derived estimations of fractional flow reserve from both CT and invasive coronary angiography. Consequently, many interventional cardiologists now wonder if the pressure wire will soon become obsolete. This head-to-head article provides a critical appraisal of recent trial data, discusses a potential evolution in how pressure wires are used and debates the motion that the device (and by extension, invasive assessment of coronary physiology) has now had its day.

Publisher

Radcliffe Media Media Ltd

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