Alcohol and Heart Failure

Author:

Rasoul Debar1ORCID,Ajay Ashwin2ORCID,Abdullah Alend3ORCID,Mathew Jean2ORCID,En Benjamin Lee Wei2ORCID,Mashida Knievel4,Sankaranarayanan Rajiv1ORCID

Affiliation:

1. Cardiology Department, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK; Liverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool, UK

2. Cardiology Department, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK

3. Cardiology Department, The Dudley Group NHS Foundation Trust, Dudley, UK

4. School of Medicine, University of Liverpool, Liverpool, UK

Abstract

Alcohol is the most frequently consumed toxic substance in the world and remains a major global public health issue, with one in three adults consuming it worldwide. Alcohol use is a leading risk factor for disease, contributing to over 60 acute and chronic health conditions, with a particularly complex association with cardiovascular disease. Chronic excessive alcohol consumption is associated with a range of cardiac complications, including decreased myocardial contractility, hypertension, arrhythmias, MI and heart failure. However, low-level alcohol consumption is believed to have a protective effect against ischaemic heart disease and diabetes. In most cohort studies, small to moderate amounts of alcohol consumption have not been linked to heart failure, indicating a threshold effect of alcohol with individual (possibly genetic) predisposition rather than a continuous effect of exposure. This review article explores the potential benefits of alcohol on the heart, the association between alcohol use and alcoholic cardiomyopathy and the epidemiology, clinical correlates and management of alcoholic cardiomyopathy.

Publisher

Radcliffe Media Media Ltd

Subject

Cardiology and Cardiovascular Medicine

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