Neuromodulatory Approaches for Atrial Fibrillation Ablation

Author:

Rodríguez-Mañero Moisés1ORCID,Martínez-Sande Jose Luis1,García-Seara Javier1,González-Ferrero Teba2,González-Juanatey José Ramón1,Schurmann Paul3,Tavares Liliana3,Valderrábano Miguel3

Affiliation:

1. Department of Cardiology, University Hospital of Santiago de Compostela, Santiago de Compostela, A Coruña, Galicia, Spain; Institute of Health Research, University of Santiago de Compostela, Santiago de Compostela, A Coruña, Galicia, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Spain

2. Department of Cardiology, University Hospital of Santiago de Compostela, Santiago de Compostela, A Coruña, Galicia, Spain

3. Methodist DeBakey Heart and Vascular Center and Methodist Hospital Research Institute, The Methodist Hospital, Houston, TX, US

Abstract

In this review, the authors describe evolving alternative strategies for the management of AF, focusing on non-invasive and percutaneous autonomic modulation. This modulation can be achieved – among other approaches – via tragus stimulation, renal denervation, cardiac afferent denervation, alcohol injection in the vein of Marshall, baroreceptor activation therapy and endocardial ganglionated plexi ablation. Although promising, these therapies are currently under investigation but could play a role in the treatment of AF in combination with conventional pulmonary vein isolation in the near future.

Publisher

Radcliffe Group Ltd

Subject

Cardiology and Cardiovascular Medicine

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