Multimodal Imaging Reveals Bilateral Idiopathic Multiple Retinal Pigment Epithelial Detachments: A Case Report

Abstract

Background: Retinal pigment epithelial detachment (RPED) is a nonspecific finding that is common in several ocular diseases; however, cases of bilateral idiopathic multiple RPEDs are rare. Less than 50 cases have been reported to date. Bilateral multiple RPEDs are usually idiopathic and benign in nature but can infrequently be associated with various ocular and systemic diseases, including central serous chorioretinopathy (CSC). The potential role of genetic factors in this condition remains elusive. We present a case where multimodal imaging assisted in revealing the diagnosis as well as discuss the potential implications of some of the genetic findings for this patient. Case report: A 30-year-old male presented with a chief complaint of mild, bilateral central blur of one-year duration. Health history was positive for type 2 diabetes mellitus. Conclusion: Multimodal ophthalmic imaging is useful in ruling out various differential diagnoses in posterior segment care, as well as monitoring for progressive changes such as sensory retinal detachment and choroidal neovascularization. Bilateral idiopathic multiple RPED is a rare condition that may represent an atypical form of CSC. There is currently no preferred treatment, besides observation, as visual prognosis is typically good.