Notch signaling partly regulates the osteogenic differentiation of retinoic acid-treated murine induced pluripotent stem cells

Author:

Osathanon Thanaphum1,Manokawinchoke Jeeranan1,Egusa Hiroshi2,Pavasant Prasit1

Affiliation:

1. Mineralized Tissue Research Unit and Craniofacial Genetics and Stem Cells Research Group, Department of Anatomy, Faculty of Dentistry, Chulalongkorn University

2. Division of Molecular and Regenerative Prosthodontics, Tohoku University Graduate School of Dentistry

Funder

National Science and Technology Development Agency

Publisher

Nihon University School of Dentistry

Subject

General Dentistry

Reference42 articles.

1. 1. Egusa H, Okita K, Kayashima H, Yu G, Fukuyasu S, Saeki M et al. (2010) Gingival fibroblasts as a promising source of induced pluripotent stem cells. PLoS One 5, e12743.

2. 2. Lou X (2015) Induced pluripotent stem cells as a new strategy for osteogenesis and bone regeneration. Stem Cell Rev 11, 645-651.

3. 3. Bilousova G, Jun du H, King KB, De Langhe S, Chick WS, Torchia EC et al. (2011) Osteoblasts derived from induced pluripotent stem cells form calcified structures in scaffolds both in vitro and in vivo. Stem Cells 29, 206-216.

4. 4. Egusa H, Kayashima H, Miura J, Uraguchi S, Wang F, Okawa H et al. (2014) Comparative analysis of mouse-induced pluripotent stem cells and mesenchymal stem cells during osteogenic differentiation in vitro. Stem Cells Dev 23, 2156-2169.

5. 5. Geling A, Steiner H, Willem M, Bally-Cuif L, Haass C (2002) A gamma-secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafish. EMBO Rep 3, 688-694.

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