Affiliation:
1. N.P. Bechterev Institute of the Human Brain of RAS
2. OOO Gamayun
3. Ivanovo State Medical University
Abstract
Primary open-angle glaucoma (POAG) is a multifactorial, progressive disease, which pathogenesis is not completely understood. This review analyzes studies that confirm the relationship between emotional state, mental characteristics, and the morphological-functional state of the central nervous system with the development and progression of POAG. The psychopathological disorders are shown to be inevitable in such chronic neurodegenerative diseases as Alzheimer's disease and glaucoma. The article presents data confirming that cognitive indicators correlate with the thickness of the retinal ganglion cell layer. Retinal ganglion cells can be considered a marker not only for glaucoma, but also for cerebral neurodegeneration, cognitive impairment, anxiety and depression levels. Optical coherence tomography of the retina can be used as a method for early detection of cognitive impairment and neurodegenerative processes in the brain. It is confirmed that patients with open-angle glaucoma need a comprehensive neurological and neuropsychological examination for early identification of cognitive disorders and timely prescription of psychotherapeutic treatment. The article also emphasizes the need for psychotherapeutic support due to the prevalence of depression, dementia, and sleep disturbances among glaucoma patients.
Publisher
Research Institute of Eye Diseases
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